Pancreatic insulinoma co-existing with gastric GIST in the absence of neurofibromatosis-1

Abstract Background Gastrointestinal stromal tumours atmas scarab (GIST) frequently occur in patients with neurofibromatosis type 1 (NF-1).It has been reported that GIST may co-exist with pancreatic endocrine tumors but this has only been in association with NF-1.Case presentation A 76 year old woman presented with a 12 month history of hypoglycaemia symptoms.

Abdominal CT scan demonstrated a 13 mm insulinoma localized in the tail of her pancreas.She was commenced on diazoxide and later underwent surgery for enucleation of insulinoma when a small ( Conclusion This is the first case report of a pancreatic insulinoma co-existing with a GIST in a patient without NF-1.In addition, we make the first report seal cookie cutter of rapidly growing cystic GIST recurrence following resection of a primary GIST tumour.

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